Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218636 | 1.00 | PTGS2 (0.38) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29592763 | 0.91 | PTGS2 (0.37) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29853214 | 0.91 | PTGS2 (0.37) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL23218673 | 0.91 | PTGS2 (0.37) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29852781 | 0.89 | PTGS2 (0.36) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL23219020 | 0.89 | PTGS2 (0.36) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL23218846 | 0.88 | CNR1 (0.37) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29853191 | 0.88 | CNR1 (0.37) | PTGS2HTTMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL23218410 | 0.88 | PTGS2 (0.39) | PTGS2HTTMAPTL3MBTL1TSHR | |
| SCHEMBL29852974 | 0.88 | PTGS2 (0.39) | PTGS2HTTMAPTL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |