Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218435 | 1.00 | KCNH2 (0.47) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL23218349 | 0.81 | PIM1 (0.49) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL23218086 | 0.80 | PIM1 (0.45) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL23218211 | 0.80 | KCNH2 (0.42) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL29852587 | 0.80 | PIM1 (0.45) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL29853267 | 0.80 | KCNH2 (0.42) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL3894812 | 0.80 | CDK9 (0.50) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL10857787 | 0.79 | KCNH2 (0.50) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL23218877 | 0.79 | KCNH2 (0.41) | KCNH2PIM1CASP6RAB9ANPC1 | |
| SCHEMBL23218189 | 0.78 | PIM1 (0.43) | KCNH2PIM1CASP6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |