Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218928 | 1.00 | TBXAS1 (0.41) | TBXAS1CFDMAPTPTGER1TP53 | |
| SCHEMBL23218656 | 0.89 | PTGER1 (0.40) | TBXAS1CFDMAPTPTGER1TP53 | |
| SCHEMBL29852614 | 0.89 | PTGER1 (0.40) | TBXAS1CFDMAPTPTGER1TP53 | |
| SCHEMBL29852978 | 0.87 | TBXAS1 (0.41) | TBXAS1CFDMAPTTP53THRB | |
| SCHEMBL23218255 | 0.87 | TBXAS1 (0.41) | TBXAS1CFDMAPTTP53THRB | |
| SCHEMBL29592551 | 0.87 | TBXAS1 (0.41) | TBXAS1CFDMAPTTP53THRB | |
| SCHEMBL23218822 | 0.86 | TBXAS1 (0.40) | TBXAS1CFDMAPTPTGER1TP53 | |
| SCHEMBL29853078 | 0.86 | TBXAS1 (0.40) | TBXAS1CFDMAPTPTGER1TP53 | |
| SCHEMBL23218270 | 0.86 | PIM1 (0.44) | TBXAS1CFDMAPTPTGER1MEN1 | |
| SCHEMBL23218485 | 0.86 | TBXAS1 (0.40) | TBXAS1CFDMAPTPTGER1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |