Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 14/20 | 0.59 |
| ▸ | F11 | P03951 | 6/20 | 0.52 |
| ▸ | TPSB2 | P20231 | 5/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218709 | 1.00 | CFD (0.59) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218070 | 0.88 | CFD (0.69) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29591968 | 0.88 | CFD (0.69) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29853072 | 0.85 | CFD (0.56) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218062 | 0.85 | CFD (0.56) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL28736702 | 0.84 | CFD (0.48) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29592574 | 0.84 | CFD (0.73) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL28736136 | 0.84 | CFD (0.73) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218632 | 0.83 | CFD (0.59) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29853108 | 0.83 | CFD (0.59) | CFDF11TPSB2PLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |