Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26768267 | 1.00 | METAP2 (0.42) | METAP2GAAPDE2AESR1ALDH1A1 | |
| SCHEMBL26767445 | 0.90 | GAA (0.40) | METAP2GAAESR1ALDH1A1MEN1 | |
| SCHEMBL26775767 | 0.89 | CYP2C9 (0.41) | METAP2GAAESR1ALDH1A1MEN1 | |
| SCHEMBL26767567 | 0.88 | GAA (0.43) | METAP2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL26775993 | 0.84 | GAA (0.43) | METAP2GAAESR1ALDH1A1MEN1 | |
| SCHEMBL26775994 | 0.84 | GAA (0.41) | METAP2GAAESR1ALDH1A1MEN1 | |
| SCHEMBL26767535 | 0.81 | JAK1 (0.38) | METAP2GAANPSR1MAPTPIK3CA | |
| SCHEMBL26767457 | 0.74 | MPI (0.46) | METAP2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30629150 | 0.74 | MPI (0.46) | METAP2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL26767565 | 0.73 | POLB (0.36) | METAP2GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119947717-A | Therapeutic use of urolithin derivatives | 范徳利亚股份公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-4284781-A1 | UROLITHIN DERIVATIVES AND METHODS OF USE THEREOF | Vandria SA (CH) | 2023-12-06 | — | — | EP | disclosed |
| CN-117015530-A | Urolithin derivatives and methods of use thereof | 范徳利亚股份公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2022162471-A1 | UROLITHIN DERIVATIVES AND METHODS OF USE THEREOF | VANDRIA SA (CH) | 2022-08-04 | — | — | WO | disclosed |