Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.58 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.58 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.58 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.58 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662695 | 1.00 | HPGD (0.59) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL11298351 | 0.83 | TNKS (0.53) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL12867892 | 0.81 | ALOX15 (0.57) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL11291776 | 0.77 | TNKS (0.47) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL40354 | 0.77 | EPHX2 (0.50) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL7372279 | 0.77 | EPHX2 (0.61) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL21623585 | 0.77 | MAPT (0.55) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL28490130 | 0.76 | TNKS (0.50) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL29689973 | 0.75 | KDM4E (1.00) | HPGDKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL29702211 | 0.75 | NPC1 (0.61) | HPGDKDM4EALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125978-A | MYC inhibitor and preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |
| WO-2022165432-A1 | CULLIN-RING E3 UBIQUITIN LIGASE 4 INHIBITOR COMPOUNDS AND METHODS OF THEIR USE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-08-04 | — | — | WO | disclosed |