Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839182 | 1.00 | ABL1 (0.36) | ABL1IRAK4TLR7ADORA2AADORA2B | |
| SCHEMBL20853046 | 0.87 | HDAC1 (0.35) | ABL1ADORA2AADORA2BP2RX3HDAC1 | |
| SCHEMBL20852915 | 0.85 | PAX8 (0.34) | ABL1IRAK4PAX8 | |
| SCHEMBL20839344 | 0.78 | TLR7 (0.34) | ABL1IRAK4TLR7ADORA2AADORA2B | |
| SCHEMBL29856049 | 0.76 | CYP17A1 (0.41) | ABL1 | |
| SCHEMBL20839184 | 0.76 | CYP17A1 (0.41) | ABL1 | |
| SCHEMBL31734141 | 0.76 | PAX8 (0.40) | ABL1TLR7ADORA2AADORA2BPAX8 | |
| SCHEMBL13047770 | 0.76 | PAX8 (0.40) | ABL1TLR7ADORA2AADORA2BPAX8 | |
| SCHEMBL29725001 | 0.74 | IRAK4 (0.35) | ABL1IRAK4ADORA2AADORA2BHDAC1 | |
| SCHEMBL19384230 | 0.74 | IRAK4 (0.35) | ABL1IRAK4ADORA2AADORA2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372455-B | Herbicidally active pyridyl-/pyrimidinyl-pyrimidine derivatives | 先正达参股股份有限公司 | 2022-10-11 | — | — | CN | disclosed |