Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337108 | 0.83 | IDO1 (0.31) | IDO1TDO2APLNRCYP1A2 | |
| SCHEMBL5708081 | 0.81 | IDO1 (0.32) | IDO1TDO2 | |
| SCHEMBL6330189 | 0.80 | APLNR (0.32) | APLNRCYP1A2 | |
| SCHEMBL27994410 | 0.76 | EPHX1 (0.40) | — | |
| SCHEMBL5708070 | 0.76 | IDO1 (0.30) | IDO1TDO2 | |
| SCHEMBL28397189 | 0.75 | IDO1 (0.32) | IDO1TDO2 | |
| SCHEMBL28397190 | 0.74 | IDO1 (0.30) | IDO1TDO2 | |
| SCHEMBL3270172 | 0.74 | IDO1 (0.35) | IDO1TDO2APLNRCYP1A2 | |
| SCHEMBL756556 | 0.73 | TSHR (0.38) | IDO1TDO2 | |
| SCHEMBL5708012 | 0.73 | CYP1A2 (0.31) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608436-B | Substituted methyl formyl reagents and methods of using same to improve physicochemical and/or pharmacokinetic properties of compounds | 斯法尔制药私人有限公司 | 2022-10-11 | — | — | CN | disclosed |