Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 10/20 | 0.78 |
| ▸ | ABL1 | P00519 | 7/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755338 | 1.00 | KIT (0.78) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL29856174 | 0.93 | KIT (0.68) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL22288302 | 0.93 | KIT (0.68) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL29856195 | 0.91 | KIT (0.79) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL28439198 | 0.91 | KIT (0.79) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL13813508 | 0.90 | KIT (0.77) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL22288273 | 0.89 | KIT (0.75) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL29856181 | 0.88 | KIT (1.00) | KITABL1FGFR1KDRCSF1R | |
| SCHEMBL4103102 | 0.88 | KIT (1.00) | KITABL1FGFR1KDRCSF1R | |
| Ammonia Solution, Strong SCHEMBL22288313 | 0.88 | KIT (0.74) | KITABL1FGFR1KDRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484482-B | Alkynyl pyrimidine or alkynyl pyridine compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |