Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8376285 | 0.95 | MAPT (0.58) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| Diethylamine SCHEMBL8377307 | 0.92 | MAPT (0.55) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL29857531 | 0.87 | ALDH1A1 (0.64) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL16755572 | 0.85 | MAPT (0.63) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL16769901 | 0.85 | MAPT (0.63) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL16755571 | 0.85 | MAPT (0.63) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL11725696 | 0.84 | DRD3 (0.74) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL11725699 | 0.84 | DRD3 (0.74) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL15562283 | 0.83 | DRD3 (0.74) | MAPTALDH1A1MAPK1RAB9ALMNA | |
| SCHEMBL16769909 | 0.83 | MAPT (0.62) | MAPTALDH1A1MAPK1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112972441-B | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2022-08-23 | — | — | CN | disclosed |