Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032380 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AMEN1KEAP1NPC1 | |
| SCHEMBL29857111 | 0.81 | POLB (0.44) | SMN1; SMN2KMT2AMEN1KEAP1NPC1 | |
| Hydrochloric Acid SCHEMBL28822255 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AMEN1KEAP1NPC1 | |
| SCHEMBL29856994 | 0.80 | PRKAB2 (0.43) | SMN1; SMN2KMT2AMEN1KEAP1BAZ2B | |
| SCHEMBL29856819 | 0.76 | LRRK2 (0.45) | SMN1; SMN2KMT2AMEN1KEAP1BAZ2B | |
| SCHEMBL5255270 | 0.76 | MEN1 (0.56) | SMN1; SMN2KMT2AMEN1KEAP1NPC1 | |
| SCHEMBL19815443 | 0.70 | CHEK2 (0.46) | SMN1; SMN2KMT2AMEN1GSK3B | |
| SCHEMBL15655702 | 0.69 | MEN1 (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL29856974 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1USP19ALDH1A1 | |
| SCHEMBL29856937 | 0.69 | MEN1 (0.42) | SMN1; SMN2KMT2AMEN1USP19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |