Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 5/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26916814 | 1.00 | MET (0.39) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL26916809 | 1.00 | MET (0.39) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL26916505 | 0.89 | JAK2 (0.41) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL26916500 | 0.89 | JAK2 (0.41) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL29857863 | 0.89 | JAK2 (0.41) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL10215045 | 0.88 | PDGFRB (0.46) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL29857797 | 0.88 | PDGFRB (0.46) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL29857648 | 0.88 | PDGFRB (0.46) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL26916323 | 0.88 | PDGFRB (0.46) | METPDGFRBKDRJAK2AAK1 | |
| SCHEMBL26916629 | 0.88 | PDGFRB (0.46) | METPDGFRBKDRJAK2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288437-A1 | MAP4K1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167627-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | WO | disclosed |