Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631428 | 1.00 | DHODH (1.00) | DHODH | |
| SCHEMBL20956423 | 1.00 | DHODH (1.00) | DHODH | |
| SCHEMBL20842872 | 0.93 | DHODH (0.86) | DHODH | |
| SCHEMBL21393927 | 0.90 | DHODH (0.82) | DHODH | |
| SCHEMBL24142242 | 0.90 | DHODH (0.84) | DHODH | |
| SCHEMBL28343272 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL24861294 | 0.90 | DHODH (0.81) | DHODH | |
| SCHEMBL19631429 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL29859506 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL20836131 | 0.89 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107382902-B | Thiazole derivative and application thereof | 华东理工大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |