Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 11/20 | 0.75 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 5/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373282 | 1.00 | WEE1 (0.75) | WEE1ALKEGFRAURKAINSR | |
| SCHEMBL21373371 | 0.94 | WEE1 (0.82) | WEE1 | |
| SCHEMBL21373403 | 0.91 | WEE1 (0.61) | WEE1EGFRKCNH2 | |
| SCHEMBL29506521 | 0.91 | WEE1 (0.61) | WEE1EGFRKCNH2 | |
| SCHEMBL21373428 | 0.88 | WEE1 (0.76) | WEE1EGFR | |
| SCHEMBL31556915 | 0.88 | WEE1 (0.76) | WEE1EGFR | |
| SCHEMBL21373294 | 0.86 | WEE1 (0.75) | WEE1 | |
| SCHEMBL21373387 | 0.86 | WEE1 (1.00) | WEE1EGFR | |
| SCHEMBL21373448 | 0.86 | WEE1 (0.61) | WEE1ALKEGFRKCNH2 | |
| SCHEMBL29506582 | 0.86 | WEE1 (0.61) | WEE1ALKEGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188802-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2022-09-15 | — | — | WO | claimed |