Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 18/20 | 0.76 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373428 | 1.00 | WEE1 (0.76) | WEE1TNK2EGFR | |
| SCHEMBL31557036 | 0.95 | WEE1 (0.69) | WEE1TNK2EGFR | |
| SCHEMBL21373401 | 0.95 | WEE1 (0.69) | WEE1TNK2EGFR | |
| SCHEMBL31557170 | 0.95 | WEE1 (0.75) | WEE1TNK2EGFR | |
| SCHEMBL21373402 | 0.95 | WEE1 (0.75) | WEE1TNK2EGFR | |
| SCHEMBL21373368 | 0.95 | WEE1 (0.80) | WEE1TNK2EGFR | |
| SCHEMBL31557290 | 0.95 | WEE1 (0.80) | WEE1TNK2EGFR | |
| SCHEMBL21373422 | 0.94 | WEE1 (0.72) | WEE1TNK2EGFR | |
| SCHEMBL31557265 | 0.94 | WEE1 (0.72) | WEE1TNK2EGFR | |
| SCHEMBL21373371 | 0.92 | WEE1 (0.82) | WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074275-A1 | COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS AND WEE1 INHIBITORS | REPARE THERAPEUTICS, INC. (CA) | 2025-04-10 | — | — | WO | disclosed |