Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 19/20 | 0.55 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326526 | 1.00 | PDE5A (0.55) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL9914175 | 0.91 | PDE5A (0.55) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL9913951 | 0.90 | PDE5A (0.68) | PDE5A | |
| SCHEMBL9913988 | 0.89 | PDE5A (0.53) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL15519933 | 0.87 | PDE5A (0.52) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL9913961 | 0.85 | PDE5A (0.58) | PDE5A | |
| SCHEMBL15520068 | 0.84 | PDE5A (0.60) | PDE5A | |
| SCHEMBL29859508 | 0.83 | PDE5A (0.51) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL9914159 | 0.83 | PDE5A (0.51) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL9913925 | 0.81 | PDE5A (0.68) | PDE5AGUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690016-B | Pyrazolopyridines and uses thereof | 广东东阳光药业有限公司 | 2022-08-12 | — | — | CN | disclosed |