Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701666 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10EPHX2L3MBTL1 | |
| SCHEMBL16785692 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL16785688 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL14437828 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL16785691 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL16785690 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL498537 | 0.77 | DPP4 (0.53) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL23611278 | 0.77 | DPP4 (0.65) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL13707354 | 0.77 | DPP4 (0.65) | KDM4EALDH1A1HSD17B10EPHX2DPP4 | |
| SCHEMBL1105086 | 0.77 | DPP4 (0.65) | KDM4EALDH1A1HSD17B10EPHX2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |