Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 9/20 | 0.50 |
| ▸ | TGM2 | P21980 | 3/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076875 | 1.00 | CES1 (0.50) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL3085898 | 0.80 | CES1 (0.62) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL29689346 | 0.80 | CES1 (0.62) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL2661276 | 0.80 | CES1 (0.47) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL14358786 | 0.80 | CES1 (0.67) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL29689423 | 0.80 | CES1 (0.67) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL2373643 | 0.80 | CES1 (0.47) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL3093497 | 0.80 | DAO (0.56) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL15228756 | 0.80 | CES1 (0.47) | CES1TGM2DAONSD2BCHE | |
| SCHEMBL30441928 | 0.80 | CES1 (0.67) | CES1TGM2DAONSD2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330941-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4452937-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2024-10-30 | — | — | EP | disclosed |
| CN-118812517-A | Antitumor compounds as UPR agonists and uses thereof | 南京圣和药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118715204-A | Compounds of formula (I) | 普赛洛私人有限公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2024175114-A1 | BORON CONTAINING COMPOUNDS AND THERAPEUTIC USES THEREOF | Shanghai Yuyao Biotech Ltd. (CN) | 2024-08-29 | — | — | WO | disclosed |
| CN-116997550-A | N- (benzoyl) -phenylalanine compounds, pharmaceutical compositions containing same and application thereof | 杭州普洛药物研究院有限公司 | 2023-11-03 | — | — | CN | disclosed |
| WO-2023115166-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| CN-114853659-A | N- (benzoyl) -phenylalanine compounds, pharmaceutical compositions containing same, and uses thereof | 普洛药业股份有限公司 | 2022-08-05 | — | — | CN | disclosed |