Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860116 | 0.80 | CES1 (0.50) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL3076875 | 0.80 | CES1 (0.50) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL30638871 | 0.78 | SMN1; SMN2 (0.43) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL32662403 | 0.78 | CA1 (0.32) | — | |
| SCHEMBL16647187 | 0.77 | CES1 (0.67) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL1092103 | 0.77 | CES1 (0.62) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL3093497 | 0.77 | DAO (0.56) | CES1ALDH1A1ALDH2ALDH3A1TGM2 | |
| SCHEMBL14358786 | 0.77 | CES1 (0.67) | CES1TGM2DAOBCHENSD2 | |
| SCHEMBL30441928 | 0.77 | CES1 (0.67) | CES1TGM2DAOBCHENSD2 | |
| SCHEMBL15228756 | 0.77 | CES1 (0.47) | CES1ALDH1A1ALDH2ALDH3A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437315-B | Thiazole bridged isoindigo receptor and polymer as well as preparation method and application thereof | 中国科学院化学研究所 | 2022-12-06 | — | — | CN | claimed |
| CN-114437315-A | Novel thiazole bridged isoindigo receptor and polymer as well as preparation method and application thereof | 中国科学院化学研究所 | 2022-05-06 | — | — | CN | claimed |
| CN-112708111-A | Novel methoxyindophenine receptor and polymer, and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-27 | — | — | CN | claimed |
| EP-4737455-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| US-20260098037-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2026-04-09 | — | — | US | disclosed |
| US-20260078131-A1 | PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 | AJAX THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260015351-A1 | METHODS AND COMPOUNDS FOR INHIBITING MKK7 ENZYMES | AXONIS THERAPEUTICS INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-RE50490-E1 | Substituted quinazoline compounds and methods of use thereof | ARAXES PHARMA LLC (US) | 2025-07-15 | — | — | US | disclosed |
| CN-120077044-A | Compounds containing multiple condensed ring structures | 正大天晴药业集团股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| WO-2025052129-A1 | PYRIDINE DERIVATIVES WHICH ACT AS INHIBITORS OF MPTP. | NRG THERAPEUTICS LTD (GB) | 2025-03-13 | — | — | WO | disclosed |
| CN-116134035-B | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20150239900-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC | 2015-08-27 | — | — | US | disclosed |
| WO-2015054572-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC (US) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015054572-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20140179682-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-20140179682-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2014-06-26 | — | — | US | disclosed |
| WO-2012170845-A2 | METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | HEFFERNAN MICHELE L R (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012170845-A2 | METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | HEFFERNAN MICHELE L R (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078131-A1 | PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 | JAK2, JAK1, JAK3 | CES1 2833/4885ALDH1A1 2846/4885ALDH2 4172/4885 |
| US-20260098037-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | SLC5A2, SLC5A11, SLC5A1 | CES1 1689/4885ALDH1A1 1814/4885ALDH2 887/4885 |
| US-20150239900-A1 | INHIBITORS OF KRAS G12C | KRAS, NRAS, HRAS | CES1 3492/4885ALDH1A1 4178/4885ALDH2 4760/4885 |
| US-20260015351-A1 | METHODS AND COMPOUNDS FOR INHIBITING MKK7 ENZYMES | PRKCSH, MAPK7, PRKCB | CES1 75/4885ALDH1A1 2835/4885ALDH2 3232/4885 |
| US-20140179682-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | GRM5, GRIK5, GRM2 | CES1 940/4885ALDH1A1 2494/4885ALDH2 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.