Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8749262 | 0.92 | MAPK1 (0.80) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL16064907 | 0.92 | MAPK1 (0.80) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8749079 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8749263 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8748863 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6881683 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8749177 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8749301 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6870643 | 0.90 | MAPK1 (0.77) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8749195 | 0.87 | MAPK1 (0.68) | MAPK1HSD11B1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022171072-A1 | DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海维申医药有限公司 | 2022-08-18 | — | — | WO | disclosed |