SCHEMBL16064907

SCHEMBL16064907

O=C(N1CCOCC1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.80
HSD11B1 P28845 6/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
LMNA P02545 2/20 0.55
ALDH1A1 P00352 2/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CNR2 P34972 1/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749262 1.00 MAPK1 (0.80) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8749301 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8749177 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8748863 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8749263 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL6881683 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8749079 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL6870643 0.98 MAPK1 (0.77) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL29860741 0.92 MAPK1 (0.73) MAPK1HSD11B1L3MBTL1LMNAALDH1A1
SCHEMBL8749195 0.91 MAPK1 (0.68) MAPK1HSD11B1L3MBTL1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220111367-A1 HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME OSAKA UNIVERSITY (JP) 2022-04-14 US disclosed
US-9883997-B2 Cosmetic compositions with tricyclodecane amides CONOPCO, INC. (US) 2018-02-06 US disclosed
US-9883997-B2 Cosmetic compositions with tricyclodecane amides CONOPCO, INC. (US) 2018-02-06 US disclosed
US-9840466-B2 Process of making adamantanamides CONOPCO, INC. (US) 2017-12-12 US disclosed
US-9840466-B2 Process of making adamantanamides CONOPCO, INC. (US) 2017-12-12 US disclosed
EP-2969026-B1 COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES UNILEVER PLC (GB) 2017-11-01 EP disclosed
US-9775793-B2 Prolonged delivery of certain fragrance components from personal care compositions CONOPCO, INC. (US) 2017-10-03 US disclosed
US-9775793-B2 Prolonged delivery of certain fragrance components from personal care compositions CONOPCO, INC. (US) 2017-10-03 US disclosed
EP-3080086-B1 PROCESS OF MAKING ADAMANTANAMIDES UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2017-07-05 EP disclosed
US-9682028-B2 Personal care photoprotective compositions with tricyclodecane amides CONOPCO, INC. (US) 2017-06-20 US disclosed
US-20160045419-A1 PERSONAL CARE PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES CONOPCO, INC., D/B/A UNILEVER (US) 2016-02-18 US disclosed
US-20160045419-A1 PERSONAL CARE PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES CONOPCO, INC., D/B/A UNILEVER (US) 2016-02-18 US disclosed
US-20160015616-A1 PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-21 US disclosed
US-20160015616-A1 PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-21 US disclosed
US-20160008249-A1 COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-14 US disclosed
US-20160008249-A1 COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-14 US disclosed
WO-2015086428-A1 PROCESS OF MAKING ADAMANTANAMIDES UNILEVER PLC (GB) 2015-06-18 WO disclosed
WO-2014139952-A2 PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS UNILEVER PLC (GB) 2014-09-18 WO disclosed
WO-2014139965-A1 PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES UNILEVER PLC (GB) 2014-09-18 WO disclosed
WO-2014139963-A1 COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES UNILEVER PLC (GB) 2014-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160015616-A1 PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS DPM1, DHCR24, POLR1C MAPK1 2835/4885HSD11B1 598/4885L3MBTL1 874/4885
US-20160045419-A1 PERSONAL CARE PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES CUTA, ERCC1, ERCC5 MAPK1 4052/4885HSD11B1 2035/4885L3MBTL1 4223/4885
US-20160008249-A1 COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES CUTA, ACMSD, LAGE3 MAPK1 3658/4885HSD11B1 1684/4885L3MBTL1 4115/4885
US-20220111367-A1 HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME SUV39H2, SUV39H1, HRH3 MAPK1 3891/4885HSD11B1 2358/4885L3MBTL1 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.