SCHEMBL29861102

SCHEMBL29861102

Nc1ccc(-c2ccc(N)c(F)c2)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.74
ALOX15 P16050 2/20 0.74
CYP3A4 P08684 2/20 0.74
ALDH1A1 P00352 3/20 0.48
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 3/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843370 0.89 HSD17B10 (0.71) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL23924225 0.86 CYP3A4 (1.00) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL105866 0.86 CYP3A4 (1.00) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL29549758 0.86 CYP3A4 (1.00) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL29365557 0.86 CYP3A4 (1.00) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL29924944 0.86 ALDH1A1 (0.62) HSD17B10ALOX15CYP3A4ALDH1A1CA12
SCHEMBL1099003 0.86 ALDH1A1 (0.62) HSD17B10ALOX15CYP3A4ALDH1A1CA12
SCHEMBL5844850 0.84 CYP3A4 (0.63) HSD17B10ALOX15CYP3A4ALDH1A1MEN1
SCHEMBL5843755 0.84 CYP3A4 (0.63) HSD17B10ALOX15CYP3A4ALDH1A1CA12
Hydrochloric Acid SCHEMBL8646655 0.84 CYP3A4 (0.94) HSD17B10ALOX15CYP3A4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890873-B Composition and method for improving imidization rate 上海邃铸科技有限公司 2024-03-19 CN claimed
CN-115678005-B Polymer, resin composition, resin film, semiconductor device, and light-emitting device 上海邃铸科技有限公司 2024-10-01 CN disclosed
CN-118440593-A Resin composition, preparation method thereof, light-emitting device and semiconductor device comprising resin composition 上海邃铸科技有限公司 2024-08-06 CN disclosed
CN-118388761-A Imidization rate accelerator, resin composition, preparation method and application thereof 上海邃铸科技有限公司 2024-07-26 CN disclosed
CN-114890873-B Composition and method for improving imidization rate 上海邃铸科技有限公司 2024-03-19 CN disclosed
CN-114014810-B Imidization rate accelerator, resin composition, preparation method and application thereof 上海邃铸科技有限公司 2023-12-26 CN disclosed
CN-115678005-A Polymer, resin composition, resin film, semiconductor device, and light-emitting device 上海邃铸科技有限公司 2023-02-03 CN disclosed
CN-114890873-A Composition and method for improving imidization rate 上海敏尧科技有限公司 2022-08-12 CN disclosed