Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458565 | 1.00 | TTR (0.59) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL23476626 | 0.94 | TTR (0.62) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL29468053 | 0.94 | TTR (0.62) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL25045481 | 0.91 | TTR (0.53) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL23458537 | 0.90 | TTR (0.56) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL29861397 | 0.90 | TTR (0.56) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL25046377 | 0.89 | TTR (0.58) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL29861448 | 0.89 | TTR (0.51) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL23458566 | 0.89 | TTR (0.51) | TTRRORCNQO1FTONAALAD2 | |
| SCHEMBL25046578 | 0.88 | TTR (0.56) | TTRRORCNQO1FTONAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069311-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing SA (CH) | 2022-10-12 | — | — | EP | disclosed |