Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458537 | 1.00 | TTR (0.56) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL25046515 | 0.92 | TTR (0.51) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL29861238 | 0.90 | TTR (0.59) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL23458565 | 0.90 | TTR (0.59) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL29861565 | 0.90 | TTR (0.49) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL23458544 | 0.90 | TTR (0.49) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL29468053 | 0.87 | TTR (0.62) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL23476626 | 0.87 | TTR (0.62) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL25046532 | 0.87 | MIF (0.46) | TTRMIFNAALAD2RORCFTO | |
| SCHEMBL25045481 | 0.84 | TTR (0.53) | TTRMIFNAALAD2RORCFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069311-A1 | REACTIVE CONJUGATES | Debiopharm Research & Manufacturing SA (CH) | 2022-10-12 | — | — | EP | disclosed |