Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 5/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27263923 | 1.00 | WEE1 (0.41) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL19508031 | 0.83 | WEE1 (0.41) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL25399238 | 0.82 | FGFR1 (0.43) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL31532094 | 0.82 | FGFR1 (0.56) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL12070065 | 0.80 | BTK (0.50) | FGFR1EGFRSRCFGFR2FGFR4 | |
| SCHEMBL29357943 | 0.80 | WEE1 (0.39) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL2261009 | 0.80 | FGFR1 (0.57) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL5061806 | 0.80 | WEE1 (0.39) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL31290940 | 0.80 | FGFR1 (0.57) | WEE1FGFR1EGFRSRCFGFR2 | |
| SCHEMBL2265749 | 0.78 | WEE1 (0.39) | WEE1FGFR1EGFRSRCFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425742-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |