Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 17/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29861918 | 1.00 | IMPDH2 (0.56) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL30190118 | 0.90 | IMPDH2 (0.54) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL21973112 | 0.82 | IMPDH2 (0.56) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL21003527 | 0.80 | IMPDH2 (0.50) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL29862038 | 0.80 | IMPDH2 (0.50) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL15828325 | 0.79 | IMPDH2 (0.49) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL30190230 | 0.79 | IMPDH2 (0.49) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| SCHEMBL21973052 | 0.76 | POLB (0.46) | IMPDH2IMPDH1KDM4EALDH1A1CYP3A4 | |
| Hericenone J SCHEMBL15828327 | 0.73 | IMPDH2 (0.77) | IMPDH2IMPDH1KDM4EALDH1A1LMNA | |
| Hericenone J SCHEMBL29862379 | 0.73 | IMPDH2 (0.77) | IMPDH2IMPDH1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187973-A1 | DOSING REGIMENS OF PHARMACEUTICAL AND NUTRACEUTICAL MUSHROOM AND CANNABIS COMPOSITIONS AND THEIR USE TO TREAT CNS DISORDERS AND IMPROVE MENTAL HEALTH | ALLIED CORP. (CA) | 2022-09-15 | — | — | WO | disclosed |