Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9889483 | 1.00 | TTR (0.73) | TTRALDH1A1TSHRARFDPS | |
| SCHEMBL15096337 | 0.85 | TTR (0.51) | TTRALDH1A1TSHRARMAPT | |
| SCHEMBL31238528 | 0.84 | TTR (1.00) | TTRALDH1A1TSHRFDPSMAPT | |
| SCHEMBL1616189 | 0.84 | TTR (1.00) | TTRALDH1A1TSHRFDPSMAPT | |
| SCHEMBL6374572 | 0.83 | FDPS (0.71) | TTRALDH1A1TSHRFDPSMAPT | |
| SCHEMBL21328349 | 0.83 | TTR (0.69) | TTRALDH1A1TSHRFDPSMAPT | |
| SCHEMBL27670275 | 0.83 | TTR (0.74) | TTRALDH1A1TSHRARFDPS | |
| SCHEMBL14667749 | 0.82 | TTR (0.49) | TTRALDH1A1TSHRARMAPT | |
| SCHEMBL6500894 | 0.82 | TTR (0.56) | TTRALDH1A1TSHRARFDPS | |
| SCHEMBL9889480 | 0.82 | AR (0.56) | TTRALDH1A1TSHRARSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630827-B | Estrogen-related receptor alpha (erra) modulators | 领先制药控股公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4045503-A1 | ESTROGEN-RELATED RECEPTOR ALPHA (ERRa) MODULATORS | Lead Pharma Holding B.V. (NL) | 2022-08-24 | — | — | EP | disclosed |