Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360272 | 1.00 | AR (0.52) | ARGPR119HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL29862967 | 0.89 | GPR119 (0.49) | GPR119KDM1AIDO1PDE4APDE4B | |
| SCHEMBL23359883 | 0.89 | GPR119 (0.49) | GPR119KDM1AIDO1PDE4APDE4B | |
| SCHEMBL29862660 | 0.88 | PDE4B (0.53) | GPR119KDM1AIDO1PDE4APDE4B | |
| SCHEMBL23360400 | 0.88 | PDE4B (0.53) | GPR119KDM1AIDO1PDE4APDE4B | |
| SCHEMBL23360295 | 0.85 | AR (0.54) | ARGPR119KDM1A | |
| SCHEMBL29862653 | 0.85 | AR (0.54) | ARGPR119KDM1A | |
| SCHEMBL2774377 | 0.84 | GPR119 (0.52) | GPR119KDM1APDE4APDE4BPDE4C | |
| SCHEMBL23707520 | 0.83 | IDO1 (0.52) | ARGPR119KDM1AIDO1PDE4A | |
| SCHEMBL23360460 | 0.83 | GPR119 (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |