Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | PAK4 | O96013 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | MELK | Q14680 | 1/20 | 0.54 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396447 | 1.00 | KMT2A (0.56) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22566519 | 0.89 | HDAC3 (0.70) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29862961 | 0.88 | TP53 (0.53) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL28401956 | 0.88 | TP53 (0.53) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22566549 | 0.86 | TSHR (0.63) | KMT2AALDH1A1LMNAMAPTCDC7 | |
| SCHEMBL29862908 | 0.85 | HDAC3 (0.54) | KMT2AKDM4EALDH1A1LMNACDC7 | |
| SCHEMBL28400450 | 0.85 | HDAC3 (0.54) | KMT2AKDM4EALDH1A1LMNACDC7 | |
| SCHEMBL28397320 | 0.84 | TP53 (0.52) | KMT2AKDM4EALDH1A1LMNAHDAC3 | |
| SCHEMBL29863344 | 0.84 | TP53 (0.52) | KMT2AKDM4EALDH1A1LMNAHDAC3 | |
| SCHEMBL29863155 | 0.82 | KDM4E (0.60) | KMT2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057015-B | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2022-09-16 | — | — | CN | claimed |
| CN-111057015-B | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2022-09-16 | — | — | CN | disclosed |