Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810270 | 1.00 | EGLN1 (0.74) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL27810327 | 0.88 | EGLN1 (0.58) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL3041133 | 0.87 | NPC1 (0.76) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL29863028 | 0.85 | NPC1 (0.74) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1031934 | 0.84 | EGLN1 (0.60) | EGLN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1035431 | 0.81 | EGLN1 (0.54) | EGLN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29862663 | 0.80 | NPC1 (0.67) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL7717500 | 0.80 | NPC1 (0.75) | EGLN1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL1499599 | 0.79 | CYP11B2 (0.71) | EGLN1NPC1MEN1KMT2AKDM4E | |
| SCHEMBL1507696 | 0.79 | MAPT (0.78) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |