Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 9/20 | 0.66 |
| ▸ | CA9 | Q16790 | 9/20 | 0.66 |
| ▸ | CA1 | P00915 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CA6 | P23280 | 4/20 | 0.65 |
| ▸ | CA7 | P43166 | 4/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.65 |
| ▸ | CA4 | P22748 | 4/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.65 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA3 | P07451 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329540 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL12284080 | 0.89 | CA12 (0.61) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL29936974 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL5859276 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL8869879 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL16410059 | 0.86 | KDM4E (0.68) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL24584918 | 0.85 | KDM4E (0.66) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL8871763 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL15932948 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL4265880 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1HPGDTP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |