SCHEMBL8869879

SCHEMBL8869879

CC(=O)COc1ccc2ccc(=O)oc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.72
ALDH1A1 P00352 6/20 0.72
HPGD P15428 2/20 0.72
HSD17B10 Q99714 2/20 0.72
TP53 P04637 1/20 0.72
CA12 O43570 7/20 0.68
CA9 Q16790 7/20 0.68
CA1 P00915 6/20 0.68
CA6 P23280 4/20 0.68
CA7 P43166 4/20 0.68
CA14 Q9ULX7 4/20 0.68
CA5B Q9Y2D0 3/20 0.68
CA4 P22748 3/20 0.68
CA5A P35218 3/20 0.68
CYP1A2 P05177 1/20 0.68
POLB P06746 3/20 0.67
MAPT P10636 2/20 0.67
MTNR1A P48039 1/20 0.66
GLA P06280 2/20 0.66
GAA P10253 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12283954 0.90 CA9 (0.67) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL29862974 0.86 KDM4E (0.72) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL14329540 0.86 KDM4E (0.72) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL20364005 0.85 CA12 (0.69) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL4265880 0.85 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL15932948 0.85 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL29936974 0.85 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL5859276 0.85 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL16410059 0.85 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10TP53
SCHEMBL15929628 0.84 KDM4E (0.67) KDM4EALDH1A1HPGDHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170227846-A1 Photopatternable Compositions and Methods of Fabricating Transistor Devices Using Same USINVEST LLC 2017-08-10 US disclosed
US-9704997-B2 Photopatternable materials and related electronic devices and methods FLEXTERRA, INC. (US) 2017-07-11 US disclosed
US-20170104080-A1 Curable Polymeric Materials and Their Use for Fabricating Electronic Devices USINVEST LLC 2017-04-13 US disclosed
US-20160190337-A1 Photopatternable Materials and Related Electronic Devices and Methods USINVEST LLC 2016-06-30 US disclosed
US-9190493-B2 Photopatternable materials and related electronic devices and methods POLYERA CORPORATION (US) 2015-11-17 US disclosed
US-20150273396-A1 DRAW SOLUTIONS AND DRAW SOLUTE RECOVERY FOR OSMOTICALLY DRIVEN MEMBRANE PROCESSES OASYS WATER, INC. 2015-10-01 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20150021597-A1 Photopatternable Materials and Related Electronic Devices and Methods USINVEST LLC 2015-01-22 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
US-5646164-A FOR THE TREATMENT OR PREVENTION OF CARDIOVASCULAR DISEASE NATIONAL SCIENCE COUNCIL (TW) 1997-07-08 US disclosed
US-4370344-A SUNSCREEN AGENT, TREATMENT OF POORIASIS ELDER PHARMACEUTICALS, INC. (US) 1983-01-25 US disclosed