Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 2/20 | 0.39 |
| ▸ | NRAS | P01111 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29863507 | 1.00 | MET (0.39) | METIRAK4PLK4NRASFLT3 | |
| Hydrochloric Acid SCHEMBL23360289 | 0.99 | MET (0.38) | METIRAK4PLK4NRASFLT3 | |
| Hydrochloric Acid SCHEMBL23360288 | 0.99 | MET (0.38) | METIRAK4PLK4NRASFLT3 | |
| Hydrochloric Acid SCHEMBL23360473 | 0.99 | MET (0.38) | METIRAK4PLK4NRASFLT3 | |
| Hydrochloric Acid SCHEMBL23359890 | 0.92 | IKBKB (0.39) | METIRAK4PLK4FLT3IRAK1 | |
| Hydrochloric Acid SCHEMBL23360060 | 0.81 | CCNT1 (0.40) | METIRAK4PLK4BRD4ATAD2 | |
| Hydrochloric Acid SCHEMBL29862951 | 0.81 | CCNT1 (0.40) | METIRAK4PLK4BRD4ATAD2 | |
| Hydrochloric Acid SCHEMBL23360062 | 0.81 | CCNT1 (0.40) | METIRAK4PLK4BRD4ATAD2 | |
| Hydrochloric Acid SCHEMBL23360559 | 0.81 | CCNT1 (0.40) | METIRAK4PLK4BRD4ATAD2 | |
| Hydrochloric Acid SCHEMBL29862981 | 0.81 | CCNT1 (0.40) | METIRAK4PLK4BRD4ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |