Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 4/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494875 | 1.00 | KRAS (0.33) | KRASSOS1 | |
| SCHEMBL24800366 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL30754558 | 0.79 | TOP1 (0.32) | KRASSOS1 | |
| SCHEMBL27093848 | 0.79 | TOP1 (0.32) | KRASSOS1 | |
| SCHEMBL29882037 | 0.79 | ADORA1 (0.36) | KRASSOS1 | |
| SCHEMBL29926474 | 0.76 | KRAS (0.48) | KRASSOS1 | |
| SCHEMBL21494905 | 0.76 | KRAS (0.48) | KRASSOS1 | |
| SCHEMBL21494871 | 0.73 | KRAS (0.52) | KRASSOS1 | |
| SCHEMBL29926561 | 0.73 | KRAS (0.52) | KRASSOS1 | |
| SCHEMBL30878232 | 0.73 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894893-A | Sulfone substituted pyrido [3,4-D ] pyrimidine derivatives for the treatment of cancer | 拜耳公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-115315424-A | 2-methyl-aza-quinazolines | 拜耳公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115028644-A | SOS1 inhibitor heterocyclic compounds | 首药控股(北京)股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-4045505-A1 | 2-METHYL-AZA-QUINAZOLINES | Bayer Aktiengesellschaft (DE) | 2022-08-24 | — | — | EP | disclosed |