Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405517 | 1.00 | MEN1 (0.51) | MEN1KMT2AHTTUCHL5GAA | |
| SCHEMBL29863008 | 0.84 | KDM4E (0.54) | MEN1KMT2AHTTUCHL5GAA | |
| SCHEMBL28405182 | 0.84 | KDM4E (0.54) | MEN1KMT2AHTTUCHL5GAA | |
| SCHEMBL29862908 | 0.78 | HDAC3 (0.54) | MEN1KMT2AUCHL5SMN1; SMN2SIRT2 | |
| SCHEMBL28400450 | 0.78 | HDAC3 (0.54) | MEN1KMT2AUCHL5SMN1; SMN2SIRT2 | |
| SCHEMBL28398052 | 0.78 | AURKA (0.48) | HTTUCHL5SIRT2HDAC3HDAC1 | |
| SCHEMBL29863097 | 0.78 | AURKA (0.48) | HTTUCHL5SIRT2HDAC3HDAC1 | |
| SCHEMBL29863344 | 0.77 | TP53 (0.52) | MEN1KMT2AUCHL5SMN1; SMN2HDAC3 | |
| SCHEMBL28397320 | 0.77 | TP53 (0.52) | MEN1KMT2AUCHL5SMN1; SMN2HDAC3 | |
| SCHEMBL29862961 | 0.76 | TP53 (0.53) | MEN1KMT2ASMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057015-B | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2022-09-16 | — | — | CN | disclosed |