Zinc Ion

Zinc Ion

SCHEMBL2986374

CCCN(CCC)C(=S)S.CCCN(CCC)C(=S)S.[S-2].[S-2].[Zn+2].[Zn+2].[Zn+2]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 1/20 0.55
CYP2E1 P05181 1/20 0.55
PTGS1 P23219 1/20 0.55
HTT P42858 1/20 0.55
GSDMD P57764 1/20 0.55
CA12 O43570 6/20 0.52
CA2 P00918 6/20 0.52
CA9 Q16790 6/20 0.52
CA1 P00915 5/20 0.52
ALDH1A1 P00352 4/20 0.34
ALDH2 P05091 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HPGD P15428 2/20 0.32
TP53 P04637 1/20 0.31
CA4 P22748 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
MGLL Q99685 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442021 0.95 HTT (0.60) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL27926635 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
SCHEMBL2233780 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Water SCHEMBL27918103 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Hydrogen Sulfide SCHEMBL7978771 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Ammonia Solution, Strong SCHEMBL9323211 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Ammonia Solution, Strong SCHEMBL6300194 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Selenium SCHEMBL11490632 0.92 HTT (0.57) ABCB11CYP2E1PTGS1HTTGSDMD
Ethylene SCHEMBL21221525 0.90 ABCB11 (0.55) ABCB11CYP2E1PTGS1HTTGSDMD
Water SCHEMBL27426640 0.90 ABCB11 (0.55) ABCB11CYP2E1PTGS1HTTGSDMD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1889897-B1 LUBRICATING GREASE COMPOSITION, ROLLING DEVICE EMPLOYING THE LUBRICATING GREASE COMPOSITION, ELECTRIC POWER STEERING APPARATUS EMPLOYING THE ROLLING DEVICE AND USE OF THE LUBRICATING GREASE COMPOSITION IN A ROLLING DEVICE JTEKT CORP (JP) 2015-08-26 EP disclosed
US-7786058-B2 Rolling device employing lubricating grease composition and electric power steering apparatus employing the rolling device JTEKT CORPORATION (JP) 2010-08-31 US disclosed
US-20090065287-A1 ROLLING DEVICE EMPLOYING LUBRICATING GREASE COMPOSITION AND ELECTRIC POWER STEERING APPARATUS EMPLOYING THE ROLLING DEVICE JTEKT CORPORATION (JP) 2009-03-12 US disclosed
EP-1889897-A1 ROLLING DEVICE EMPLOYING LUBRICATING GREASE COMPOSITION AND ELECTRIC POWER STEERING APPARATUS EMPLOYING THE ROLLING DEVICE JTEKT Corporation (JP) 2008-02-20 EP disclosed