Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968398 | 0.83 | HTRA1 (0.52) | HTRA1NPC1MEN1KMT2ACYP3A4 | |
| SCHEMBL30147198 | 0.81 | HTRA1 (0.66) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL7307343 | 0.81 | HTRA1 (0.63) | HTRA1NPC1MEN1KMT2ACYP3A4 | |
| SCHEMBL29865605 | 0.80 | NPC1 (0.56) | NPC1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL1243964 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL2239296 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL5201925 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL205497 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL4195796 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB | |
| SCHEMBL9543379 | 0.79 | HTRA1 (0.60) | HTRA1MEN1KMT2ACYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066417-B | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-115066417-A | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |