⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26441538 | 0.90 | — | — | |
| SCHEMBL15929572 | 0.90 | — | — | |
| SCHEMBL10163922 | 0.87 | — | — | |
| SCHEMBL12199046 | 0.87 | — | — | |
| SCHEMBL18194669 | 0.87 | — | — | |
| SCHEMBL11834983 | 0.84 | CA2 (0.35) | — | |
| SCHEMBL17888104 | 0.83 | — | — | |
| SCHEMBL31682148 | 0.81 | CA2 (0.32) | — | |
| SCHEMBL15755135 | 0.81 | — | — | |
| SCHEMBL4107663 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428396-B2 | Fused pyridine ring derivative, preparation method therefor, and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2025-09-30 | — | — | US | disclosed |
| CN-114929685-B | Fused pyridine ring derivatives, preparation method thereof and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20230023968-A1 | FUSED PYRIDINE RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| EP-4067349-A1 | FUSED PYRIDINE RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2022-10-05 | — | — | EP | disclosed |
| CN-114929685-A | Fused pyridine ring derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |