Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29866672 | 0.88 | PDE10A (0.40) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL29866010 | 0.83 | PDE10A (0.36) | PDE10ACYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL25897398 | 0.81 | DRD4 (0.43) | CYP1A2CYP2C9CYP2C19POLBLMNA | |
| SCHEMBL31607262 | 0.81 | DRD4 (0.43) | CYP1A2CYP2C9CYP2C19POLBLMNA | |
| SCHEMBL30697029 | 0.79 | TDP1 (0.34) | CYP1A2CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL29136423 | 0.77 | CHRM2 (0.39) | POLBLMNAPAX8MEN1KMT2A | |
| SCHEMBL29865942 | 0.77 | CHRM2 (0.39) | POLBLMNAPAX8MEN1KMT2A | |
| SCHEMBL26677657 | 0.75 | MAPT (0.39) | CYP1A2CYP2C9CYP2C19POLBLMNA | |
| SCHEMBL29866372 | 0.75 | GAA (0.37) | CYP1A2CYP2C9CYP2C19LMNARAB9A | |
| SCHEMBL25573065 | 0.75 | GAA (0.37) | CYP1A2CYP2C9CYP2C19LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294806-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022175746-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |