Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865942 | 1.00 | CHRM2 (0.39) | CHRM2HTR1ACHRM1DRD2HTR2A | |
| SCHEMBL29866682 | 0.86 | CHRM2 (0.37) | CHRM2HTR1ACHRM1DRD2HTR2A | |
| SCHEMBL30663579 | 0.82 | CHRM2 (0.36) | CHRM2HTR1ACHRM1DRD2HTR2A | |
| SCHEMBL29865894 | 0.81 | PDE10A (0.32) | — | |
| SCHEMBL27107024 | 0.80 | KCNH2 (0.37) | CHRM2HTR1ACHRM1DRD2HTR2A | |
| SCHEMBL30663590 | 0.80 | GABRG2 (0.41) | MEN1KMT2A | |
| SCHEMBL30663578 | 0.78 | HTR5A (0.35) | — | |
| SCHEMBL29136434 | 0.78 | HTR5A (0.35) | — | |
| SCHEMBL29865871 | 0.77 | PDE10A (0.41) | CHRM1DRD2HTR2CHRH1OPRK1 | |
| SCHEMBL30663589 | 0.77 | LMNA (0.41) | CHRM2HTR1ACHRM1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120440-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-11-24 | — | — | CN | disclosed |