Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.61 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289917 | 0.82 | CDC7 (0.62) | CDC7DBF4MAPTNPC1RAB9A | |
| SCHEMBL288491 | 0.80 | CDC7 (0.60) | CDC7DBF4RXFP1POLBNPSR1 | |
| SCHEMBL298267 | 0.78 | CDC7 (0.65) | CDC7DBF4RXFP1POLBNPSR1 | |
| SCHEMBL274346 | 0.78 | CDC7 (0.59) | CDC7DBF4POLBMAPTHDAC3 | |
| Hydrochloric Acid SCHEMBL1519816 | 0.76 | CDC7 (0.57) | CDC7DBF4POLBMAPTNPC1 | |
| SCHEMBL23794795 | 0.76 | CDC7 (0.79) | CDC7DBF4MAPTNPC1PKM | |
| SCHEMBL5735273 | 0.76 | CDC7 (1.00) | CDC7DBF4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2225549 | 0.76 | CDC7 (0.79) | CDC7DBF4NPSR1MAPTNPC1 | |
| SCHEMBL290424 | 0.76 | CDC7 (0.52) | CDC7DBF4MAPTNPC1RAB9A | |
| SCHEMBL64687 | 0.76 | HDAC3 (0.58) | CDC7DBF4RXFP1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010065383-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-06-10 | — | — | WO | disclosed |