Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958438 | 0.98 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC6CES2 | |
| SCHEMBL7018973 | 0.86 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC6HPGD | |
| SCHEMBL1164276 | 0.82 | CES2 (0.60) | HDAC3HDAC4HDAC1HDAC6CES2 | |
| SCHEMBL2659566 | 0.81 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC6DAO | |
| SCHEMBL28383825 | 0.80 | CES2 (0.52) | HDAC3HDAC4HDAC1HDAC6CES2 | |
| SCHEMBL19224033 | 0.80 | CES2 (0.47) | HDAC3HDAC4HDAC1HDAC6CES2 | |
| SCHEMBL490430 | 0.80 | GSK3B (0.54) | CES2CES1DAOGSK3BHPGD | |
| SCHEMBL2279695 | 0.79 | CES2 (0.45) | HDAC3HDAC4HDAC1HDAC6CES2 | |
| SCHEMBL7640681 | 0.79 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC6HPGD | |
| SCHEMBL5068414 | 0.79 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 391 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939829-B | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2023-02-21 | — | — | CN | claimed |
| CN-112939829-A | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2021-06-11 | — | — | CN | claimed |
| WO-2011023791-A2 | METHOD FOR PRODUCING ORGANOALUMINIUM COMPOUNDS AND USE THEREOF | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2011-03-03 | — | — | WO | claimed |
| US-20260053393-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20250230174-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-12285250-B2 | Near-IR glucose sensors | PROFUSA, INC (US) | 2025-04-29 | — | — | US | disclosed |
| US-20250009915-A1 | NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF | FUJIFILM CORPORATION (JP) | 2025-01-09 | — | — | US | disclosed |
| US-20240376085-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2024-11-14 | — | — | US | disclosed |
| EP-4408530-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| CN-116023359-B | Synthesis method of aminothiophene compound and aminothiophene compound | 上海泰坦科技股份有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118119613-A | Benzimidazoles as IL-17 modulators | 詹森药业有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-1024006-C | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGEN INC (US) | 1994-03-16 | — | — | CN | disclosed |
| US-5234926-A | Skin disorders | ALLERGAN, INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5089509-A | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0272921-B1 | ETHYNYLHETEROAROMATIC ACIDS HAVING RETINOIC ACID-LIKE ACTIVITY | ALLERGAN, INC (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4980484-A | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGAN, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| US-4927947-A | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGAN, INC. (US) | 1990-05-22 | — | — | US | disclosed |
| US-4923884-A | Ethynylheteroaromatic-acids having retinoic acid-like activity | ALLERGAN, INC. (US) | 1990-05-08 | — | — | US | disclosed |
| CN-87107535-A | Ethynyl heteroaromatic carboxylic acids with retinoid activity | — | 1988-08-31 | — | — | CN | disclosed |
| EP-0272921-A1 | Ethynylheteroaromatic acids having retinoic acid-like activity | ALLERGAN, INC (US) | 1988-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230174-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | HDAC3 1530/4885HDAC4 2021/4885HDAC1 2343/4885 |
| US-20260053393-A1 | NEAR-IR GLUCOSE SENSORS | INSR, IRS1, SLC2A4 | HDAC3 246/4885HDAC4 997/4885HDAC1 1270/4885 |
| US-12285250-B2 | Near-IR glucose sensors | IRS1, SLC2A4, GPR119 | HDAC3 1790/4885HDAC4 765/4885HDAC1 1557/4885 |
| US-20250009915-A1 | NOVEL NITROGEN-CONTAINING COMPOUND OR SALT THEREOF, OR METAL COMPLEX THEREOF | SLC39A3, SLC39A14, SLC39A11 | HDAC3 194/4885HDAC4 407/4885HDAC1 90/4885 |
| US-20240376085-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | IL17A, IL23R, IL4I1 | HDAC3 165/4885HDAC4 171/4885HDAC1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.