Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490479 | 0.91 | NPSR1 (0.40) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17490478 | 0.87 | ALDH1A1 (0.42) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL18979043 | 0.86 | ALDH1A1 (0.41) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18978915 | 0.84 | ALDH1A1 (0.40) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18978911 | 0.82 | KDM4E (0.38) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL18978910 | 0.82 | KDM4E (0.38) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30459706 | 0.79 | ALDH1A1 (0.43) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17490420 | 0.79 | KDM4E (0.33) | KDM4EGAA | |
| SCHEMBL28359039 | 0.78 | NPSR1 (0.45) | NPSR1LMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28359193 | 0.78 | POLB (0.45) | NPSR1LMNAALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642838-B | EGFR inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |