Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25267520 | 1.00 | EGFR (0.39) | EGFRCA1CA2L3MBTL1CA9 | |
| Hydrochloric Acid SCHEMBL21225281 | 0.98 | L3MBTL1 (0.41) | EGFRCA1CA2L3MBTL1CA9 | |
| SCHEMBL25607369 | 0.77 | EGFR (0.39) | EGFRL3MBTL1ALDH1A1HTTKDM1A | |
| SCHEMBL8115905 | 0.77 | HTT (0.40) | EGFRL3MBTL1ALDH1A1HTTCTSL | |
| SCHEMBL147626 | 0.77 | EGFR (0.39) | EGFRL3MBTL1ALDH1A1POLBTDP1 | |
| Hydrochloric Acid SCHEMBL28339215 | 0.77 | KDM1A (0.38) | CA1CA2L3MBTL1CA9ALDH1A1 | |
| SCHEMBL29544314 | 0.76 | PTGES2 (0.41) | EGFRCA1CA2L3MBTL1CA9 | |
| SCHEMBL3231386 | 0.76 | PTGES2 (0.41) | EGFRCA1CA2L3MBTL1CA9 | |
| SCHEMBL31556317 | 0.76 | CA1 (0.40) | EGFRCA1CA2L3MBTL1CA9 | |
| SCHEMBL29573356 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532485-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| WO-2024042361-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2024-02-29 | — | — | WO | disclosed |
| WO-2023227946-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-11-30 | — | — | WO | disclosed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |