Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26914818 | 1.00 | KMT2A (0.46) | KMT2AIRAK4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16961921 | 0.86 | GAA (0.40) | KMT2AHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1286684 | 0.84 | IRAK4 (0.53) | KMT2AIRAK4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13265348 | 0.83 | KMT2A (0.43) | KMT2AIRAK4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2481524 | 0.81 | KMT2A (0.42) | KMT2AIRAK4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7787275 | 0.80 | SMN1; SMN2 (0.51) | KMT2AHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16950472 | 0.80 | GAA (0.37) | KMT2AHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16960079 | 0.79 | GAA (0.36) | KMT2AHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22646881 | 0.76 | HTT (0.44) | KMT2AIRAK4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12845255 | 0.76 | KCNK3 (0.49) | KMT2ASMN1; SMN2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907341-A | Pyridopyrimidinone derivatives, and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-08-16 | — | — | CN | disclosed |