Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950338 | 0.86 | GAA (0.40) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1286684 | 0.84 | IRAK4 (0.53) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29867597 | 0.83 | KMT2A (0.46) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL26914818 | 0.83 | KMT2A (0.46) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2481524 | 0.81 | KMT2A (0.42) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL18257237 | 0.79 | DRD1 (0.39) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL698393 | 0.78 | LMNA (0.53) | KMT2ALMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL15108831 | 0.76 | KDM4E (0.47) | KMT2AALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL27933650 | 0.75 | IRAK4 (0.56) | KMT2AALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL21132607 | 0.74 | TSHR (0.37) | KMT2AALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |