SCHEMBL29867900

SCHEMBL29867900

C#CCCNCCOCCOCCOCCOC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 12/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26879907 0.88 ASGR1 (0.57) ASGR1
SCHEMBL24256177 0.83 ASGR1 (0.65) ASGR1
SCHEMBL26879913 0.83 ASGR1 (0.65) ASGR1
SCHEMBL30287658 0.82 ASGR1 (0.59) ASGR1
SCHEMBL25867243 0.79 ASGR1 (0.57) ASGR1
SCHEMBL25867253 0.79 ASGR1 (0.57) ASGR1
SCHEMBL24256002 0.79 ASGR1 (0.55) ASGR1
SCHEMBL26879886 0.79 ASGR1 (0.60) ASGR1
SCHEMBL26889339 0.78 ASGR1 (0.52) ASGR1
SCHEMBL24256015 0.78 ASGR1 (0.53) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115066438-A ASGPR binding compounds for degrading extracellular proteins 阿维拉治疗公司 2022-09-16 — — CN disclosed
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