Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650433 | 0.81 | LMNA (0.47) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL25309758 | 0.80 | LMNA (0.48) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL1566074 | 0.80 | LMNA (0.48) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL25308726 | 0.80 | LMNA (0.48) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL417603 | 0.80 | LMNA (0.48) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL25307033 | 0.79 | LMNA (0.45) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL25306201 | 0.79 | LMNA (0.45) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL30063100 | 0.78 | TAAR1 (0.47) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL10420228 | 0.77 | LMNA (0.54) | LMNAHRH3HRH4TAAR1TSHR | |
| SCHEMBL19559233 | 0.77 | LMNA (0.54) | LMNAHRH3HRH4TAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |