Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397225 | 0.88 | ALDH1A1 (0.78) | ALDH1A1GAAIDO1POLBNPC1 | |
| SCHEMBL10845124 | 0.82 | ALDH1A1 (0.69) | ALDH1A1GAAIDO1POLBNPC1 | |
| SCHEMBL1176806 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAANPC1MAPTNPSR1 | |
| SCHEMBL1772596 | 0.75 | CYP2C9 (0.64) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1974952 | 0.74 | KDM4E (0.60) | ALDH1A1GAAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL9822717 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GAAIDO1MAPTRECQL | |
| SCHEMBL9788316 | 0.72 | ALDH1A1 (0.56) | ALDH1A1GAAIDO1POLBMAPT | |
| SCHEMBL28456734 | 0.72 | ALDH1A1 (0.56) | ALDH1A1GAAIDO1POLBMAPT | |
| SCHEMBL3018475 | 0.72 | GAA (0.62) | ALDH1A1GAAIDO1POLBNPC1 | |
| SCHEMBL3936548 | 0.72 | GAA (0.62) | ALDH1A1GAAIDO1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294804-B1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2026-04-08 | — | — | EP | disclosed |
| CN-117440951-A | Pyridone compounds and methods of use | 埃克塞里艾克西斯公司 | 2024-01-23 | — | — | CN | disclosed |
| EP-4294804-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | Exelixis, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022178205-A1 | PYRIDONE COMPOUNDS AND METHODS OF USE | EXELIXIS, INC. (US) | 2022-08-25 | — | — | WO | disclosed |