Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705082 | 0.97 | KMT2A (0.54) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL30824717 | 0.97 | KMT2A (0.54) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL30064257 | 0.97 | KMT2A (0.54) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL30670380 | 0.89 | MAPT (0.58) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL13248200 | 0.89 | MAPT (0.58) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL4427988 | 0.88 | MAPT (0.57) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL31481345 | 0.88 | MAPT (0.57) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL581227 | 0.86 | HCAR3 (0.73) | MAPTALDH1A1HCAR3PKMPTGER4 | |
| SCHEMBL23705089 | 0.85 | MAPT (0.57) | MAPTKDM4EALDH1A1HCAR3KMT2A | |
| SCHEMBL20402644 | 0.85 | MAPT (0.57) | MAPTKDM4EALDH1A1HCAR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897177-A | Molecular degradation agent for extracellular proteins | 耶鲁大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |